Deferroxamine Preconditioning Promotes Long-Lasting Retinal Ischemic Tolerance
نویسندگان
چکیده
منابع مشابه
Deferroxamine preconditioning promotes long-lasting retinal ischemic tolerance.
OBJECTIVE "Ischemic tolerance" can be induced in the retina by "preconditioning" with brief periods of non-injurious retinal ischemia or systemic hypoxia. The present study was undertaken to assess whether tolerance can be induced pharmacologically by deferroxamine (DFX), an iron chelator, which promotes the expression of the transcription factor, hypoxia-inducible factor 1-alpha (HIF-1alpha), ...
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ژورنال
عنوان ژورنال: Journal of Ocular Pharmacology and Therapeutics
سال: 2008
ISSN: 1080-7683,1557-7732
DOI: 10.1089/jop.2008.0082